203361681 – Formulation Design and Development Scientist – Permanent

Permanent
Job Description

Category: Medical/Pharmaceutical/Scientific

Full Time – 2020-07-17 15:07:44
Consider joining Eurofins, where people are the most important element in our business. Eurofins is a leading contract research organisation providing testing and research services in the pharmaceutical and biopharmaceutical sciences to clients worldwide. Our innovative Professional Scientific Services (PSS) programme engages full-time scientists, analysts, technicians and technical support personnel managed by Eurofins directly at the client facility, to provide long term service needs while maintaining the same services, expertise and cGMP compliance available at the Eurofins facility. This multi award-winning programme offers excellent career opportunities for people who have a proven track record in combining excellent technical ability, with first class interpersonal and communication skills. We are currently recruiting for enthusiastic and innovative research scientists in formulation design and development of clinical and commercial dosage forms. These are new and exciting opportunities based at our client’s facility, a top tier pharmaceutical company in Sandwich, Kent, UK. The purpose of these roles is to participate alongside the client in the design and analysis of parenteral dosage forms at all stages of development. Job Responsibilities May include but will not be exclusive to the following and will be based on the applicant’s experience and client’s requirements. •To design and undertake high quality scientific experimentation to further the formulation and process development of parenteral dosage forms for novel drug candidates. •To contribute to the definition of processes for sterile manufacture of clinical supplies and/or commercial drug product. •To provide technical support to multidisciplinary teams in order to facilitate and influence the development of quality sterile drug products – particular focus on characterisation of liquid dosage forms and resolution of associated technical challenges. •To independently participate in aspects of experimental design and perform hands-on laboratory experiments using small scale manufacturing technologies, such as aseptic solution compounding and lyophilisation. •To assess the chemical and physical stability of formulations in collaboration with analytical departments and to identify the root cause of potential stability, manufacturability and performance issues. •To interpret scientific data to derive clear conclusions and provide direction for future work. •To communicate effectively to the project team and present data at team meetings. •To maintain high quality documentation of all activities in electronic notebooks, reports as required. Experience & Qualifications •Degree in pharmaceutical or allied sciences (i.e. first degree in pharmacy, pharmaceutical technology, chemistry, chemical engineering, life sciences) or similar, plus a minimum of 1 year’s relevant industry experience is essential. Alternatively a relevant, recent post-graduate qualification will also be considered. •A sound, fundamental knowledge of chemistry, in a formulation context is essential. In addition, practical experience in the following is highly desirable – characterisation of liquid dosage forms, resolution of associated technical challenges, a good understanding of fate of active pharmaceutical ingredient in drug product and a good understanding of soft matter structures (e.g. liquid crystals). •Practical work experience in an operational R&D role in pharmaceutical/drug delivery or allied industries, e.g. pre-formulation, formulation and/or process development of liquid dosage forms (sterile and/or non-sterile). Alternatively, similar practical experience gained from a postgraduate qualification (e.g. PhD). •Broad scientific knowledge base and technical ability with formulation, processing and characterisation of sterile/non-sterile liquid dosage forms. •Good experimentalist with evidence of general competence in a range of laboratory skills/techniques and unit operations in a manufacturing environment relevant to sterile parenteral and non-sterile oral products. •Good awareness/understanding of the requirements for working in a GCP and/or GMP environment, knowledge of drug development and clinical trial processes would be an advantage. •Evidence of experience in autonomous planning, performing and reporting of own experimental programmes, including demonstrated proficiency in background literature searching, interpretation and application of findings. •Effective oral and written presentation skills, with proficiency in use of standard word processing, presentation and spreadsheet software packages.

203361681